These things are engraved on items at the moment of their creation by a crafter. The crafter may have the engraving/blessing ability, or he may have a priest standing by to aid him. Runes may be put on weapons, and Ancient Words may be put on specific armor pieces.
Inscribe Holy Rune: These runes include runes of healing, balance, stamina regeneration, and heightened morale.
Inscribe Evil Rune: These runes include runes that sap strength, health, and lower enemy morale.